Paget's disease of bone most commonly occurs in the pelvis, skull, spine, and legs. Risk factors include increasing age and a family history of the condition. Over time, affected bones may become fragile and misshapen.

This condition can be symptomless for a long period of time. When symptoms do occur, they may include bone deformities, broken bones, and pain in the affected area.

Treatment involves medications that reduce the breakdown of bone.

A disease that disrupts the replacement of old bone tissue with new bone tissue.

Consult a doctor for medical advice

Sources:  Mayo Clinic and others.

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Cases per year

More than 200,000 US cases per year

Treatment can help, but this condition can't be cured

Requires a medical diagnosis

Lab tests or imaging always required

Chronic: can last for years or be lifelong

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